- Figure 38
Nocturnal noninvasive ventilation in addition to rehabilitation in hypercapnic COPD patients
This Figure presents the results of a study from the Netherlands that compared nocturnal NIV (nasal intermittent positive pressure ventilation [NIPPV]) in addition to pulmonary rehabilitation in hypercapnic patients with COPD versus pulmonary rehabilitation without nocturnal NIV.[19] The left panel shows changes in health-related quality of life, which were assessed by the use of the Severe Respiratory Insufficiency questionnaire.[5] Although there was an increase in health-related quality of life for the patients receiving pulmonary rehabilitation without NIV, the increases were significantly higher once these patients were also receiving nocturnal NIV. With a mean inspiratory positive airway pressure (IPAP) of 20 cmH2O and a mean breathing frequency of 18 breaths per minute during NIV, PaCO2 was significantly reduced in the group using NIPPV but not in the group receiving only pulmonary rehabilitation.
References
Windisch W, Freidel K, Schucher B, et al. The Severe Respiratory Insufficiency (SRI) Questionnaire: a specific measure of health-related quality of life in patients receiving home mechanical ventilation. J Clin Epidemiol. 2003;56:752–759.
Duiverman ML, Wempe JB, Bladder G, et al. Nocturnal noninvasive ventilation in addition to rehabilitation in hypercapnic COPD patients. Thorax 2008;63:1052–1057.