Rader - Figure 26 - Pedigree Text

Rader - Figure 26 - Pedigree

This Figure repeats Figure 4, the patient's pedigree, which suggested that there wasn't a clear dominant family history of hypercholesterolemia.  This led to some uncertainty as to how to diagnose this patient's disease, and this suggested that this might be a case where it would be reasonable to sequence his LDL receptor as a way of better understanding what the diagnosis should be.  This should also lead to better management of his overall family structure in terms of identifying who might be at risk.
Rader J Clin Lipidol. 2012;