Somers - Figure 50
Hypoxemia and Prognosis after MI
FIG. 50: The data in the previous Figure showed that for patients with sleep apnea, a heart attack is more likely to occur during the nighttime hours. The other finding from the same group was that about 60% of the patients with an MI had previously undiagnosed OSA.
So the question is, Does the OSA, diagnosed or not, in a patient who has had an MI and survived, have an impact on the future outcome of that patient?
Shown in this Figure are the data from a follow-up of about 4 years in the 44% of patients who had sleep disordered breathing (SDB).[37] As seen in the Figure, for patients in the highest tertile of oxygen desaturation, with oxygen saturation ≤84% during sleep, the likelihood of a major adverse cardiovascular event (MACE) increased significantly compared to patients apnea in the middle tertile of oxygen desaturation or those who had minimal, if any, nighttime desaturation.
References
Xie J, Sert Kuniyoshi FH, Covassin N, et al. Nocturnal hypoxemia due to obstructive sleep apnea is an independent predictor of poor prognosis after myocardial infarction. J Am Heart Assoc. 2016;5:e003162.
