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- Figure 40

Baseline Sleep Apnea and LVEF Data

FIG. 40:  Finally, ADVENT-HF is a study in which most patients to date have OSA (66% have predominant OSA versus only 34% with predominant CSA).  The mean LVEF is approximately 33%, which is identical to the SERVE-HF trial.[15] 

The ADVENT-HF trial has no yet been completed, and there are certainly more challenges ahead.  

Bradley D. Chest 2016;00.

References

[15]

Cowie MR, Woehrle H, Wegscheider K, et al. Adaptive servo-ventilation for central sleep apnea in systolic heart failure. N Engl J Med. 2015;373:1095–1105.