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Won - Figure 24

Patients on Chronic Opioids

FIG. 24:  This Figure shows the design of a recent study of ASV therapy in patients with Op-CSA by Javaheri and colleagues.[18]  The subjects were 20 patients on chronic opioids who were sent to the sleep center for evaluation for OSA; 5 (20%) had pure OSA, but the other 16 (80%) had OSA complicated by CSA.  Of these 16, 25% responded to initial CPAP and 20% of the non-responders responded to CPAP after 4–8 weeks, but the remainder of the non-responders had persistent CSA despite long-term CPAP use.  All these patients were then assigned to ASV therapy.  

Won C. Chest 2016;00.

References

[18]

Javaheri S, Harris N, Howard J, Chung E. Adaptive servoventilation for treatment of opioid-associated central sleep apnea. J Clin Sleep Med. 2014;10:637–643.