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Won - Figure 20

CPAP

FIG. 20:  There are several studies looking at PAP use in Op-CSA.  CPAP has been explored in several small studies of chronic opioid users,[14-19] but the results have been disappointing.  Central apneas often persisted on CPAP therapy and in some cases CPAP even worsened the CSA index (CAI).  

Won C. Chest 2016;00.

References

[14]

Farney RJ, Walker JM, Boyle KM, et al. Adaptive servoventilation (ASV) in patients with sleep disordered breathing associated with chronic opioid medications for non-malignant pain. J Clin Sleep Med. 2008;4:311–319. 

[15]

Javaheri S, Malik A, Smith J, Chung E. Adaptive pressure support servoventilation: a novel treatment for sleep apnea associated with use of opioids. J Clin Sleep Med. 2008;4:305–310. 

[16]

Alattar M, Scharf S. Opioid-associated central sleep apnea: a case series. Sleep Breath. 2009;13:201–206. 

[17]

Ramar K, Ramar P, Morgenthaler T. Adaptive servoventilation in patients with central or complex sleep apnea related to chronic opioid use and congestive heart failure. J Clin Sleep Med. 2012;8:569–576. 

[18]

Javaheri S, Harris N, Howard J, Chung E. Adaptive servoventilation for treatment of opioid-associated central sleep apnea. J Clin Sleep Med. 2014;10:637–643.

[19]

Troitino A, Labedi N, Kufel T, El-Solh AA. Positive airway pressure therapy in patients with opioid-related central sleep apnea. Sleep Breath. 2014;18:367–373.

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