Burger - Figure 32
No proven role neo-/adjuvant chemo
FIG. 32: Non-urachal adenocarcinomas are often flat lesions presenting as a diffuse thickening of the bladder wall in every position of the bladder.[7] This cancer is considered highly aggressive. In non-invasive cases, TURB or partial cystectomy is debated, but is probably not the most appropriate choice for every case, since it is clear that invasive cases do require cystectomy.[18] To date, recommended chemotherapy regimens have not been defined, but ifosfamide, paclitaxel, and cisplatin have been suggested.
References
Klaile Y, Schlack K, Boegemann M, et al. Variant histology in bladder cancer: how it should change the management in non-muscle invasive and muscle invasive disease? Transl Androl Urol. 2016;5:692−701 https://dx.doi.org/10.21037%2Ftau.2016.06.13
Wright JL, Porter MP, Li CI, et al. Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder. Cancer. 2006;107:721−8 https://doi.org/10.1002/cncr.22059
