Burger - Figure 39
Small Cell Carcinoma Data
FIG. 39: Sarcomatoid bladder carcinoma is even more rare than the other variants reviewed above, comprising only 0.3% of bladder cancer cases, although 5 sarcomatoid features are being found in up to 6% of bladder cancer patients.[7,22,23] Sarcomatoid carcinoma also has a poor prognosis and marked aggressiveness. Most cases are invasive. Following upfront cystectomy, the 2-year survival rate is about 50%, but data are scarce, and no conclusions can be drawn about neoadjuvant chemotherapy.
References
Klaile Y, Schlack K, Boegemann M, et al. Variant histology in bladder cancer: how it should change the management in non-muscle invasive and muscle invasive disease? Transl Androl Urol. 2016;5:692−701 https://dx.doi.org/10.21037%2Ftau.2016.06.13
Wright JL, Black PC, Brown GA, et al. Differences in survival among patients with sarcomatoid carcinoma, carcinosarcoma and urothelial carcinoma of the bladder. J Urol. 2007;178:2302−6
Malla M, Wang JF, Trepeta R, et al. Sarcomatoid carcinoma of the urinary bladder. Clin Genitourin Cancer. 2016;14:366−72 http://dx.doi.org/10.1016/j.clgc.2016.03.004
