Burger - Figure 50

Is Radical Cystectomy necessary for all patients with non-muscle-invasive micropapillary bladder cancer?

FIG. 50:  Variants are not all rare and they usually indicate a poor prognosis. So first, we need to be aware of them and we need to ask for pathology review.  We need to talk to our pathologist colleagues about the possibility that a variant might be present in some cases, and if it is present, we should choose more aggressive treatment and, wherever possible, consider participation in trials. 

I hope that this has given you some insight of variants in NMI bladder cancer despite the rarity of the data, but I hope I have convinced you that variants do matter overall.