Stenzl - Figure 12
mRNA Expression
FIG. 12: Several years ago a group in Lund, Sweden, developed a new molecular subtyping-based classification that divided urothelial cancer into 5 major subtypes: urobasal A, urobasal B, genomically instable, squamous cell carcinoma-like, and infiltrative (Figure).[3] The classification was based on different patterns of immune infiltration of the tumor, different appearances in the cell cycle, cell adhesion, cytokeratin signature, and receptor tyrokinase gene expression, all of which were independent of the pathological classification.
References
[3]
Sjödahl G, Lauss M, Lövgren K, Chebil G, et al. A molecular taxonomy for urothelial carcinoma. Clin Cancer Res. 2012;18:3377−86 https://doi.org/10.1158/1078-0432.CCR-12-0077-T
