Stenzl - Figure 22

Molecular Subtypes of Muscle-invasive Bladder Cancer

FIG. 22:  As described in Figure 14, Choi and others at MD Anderson Cancer Center (Houston, Texas, USA) have developed a classification of tumors based on molecular staging using the terms “basal muscle-invasive bladder cancer” versus “luminal muscle invasive bladder cancer," with a subgroup of p53-like tumors in between.[5,18]  

References

[5]

Choi W, Porten S, Kim S, et al. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell. 25, 152–65  http://dx.doi.org/10.1016/j.ccr.2014.01.009

[18]

Choi W, Czerniak B, Ochoa A, et al. Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer. Nature Rev Urol. 2014;11:400–10. doi:10.1038/nrurol.2014.129