Grossman - Figure 26
Medical Quality is Important
FIG. 26: Medical quality is also important. This is supported by these data from a multinational study.[13] In patients who received optimal neoadjuvant chemotherapy, overall survival was dramatically better than in patients receiving suboptimal or no neoadjuvant chemotherapy (right-hand graph). It is important to note that when patients receive suboptimal neoadjuvant chemotherapy their overall survival is similar to that in patients who get no neoadjuvant chemotherapy. So if treatment is to be neoadjuvant chemotherapy, then it must be given with sufficient intensity, meaning it must be high-quality chemotherapy.
References
Hinata N, Hussein AA, George S, et al. Impact of suboptimal neoadjuvant chemotherapy on peri-operative outcomes and survival after robot-assisted radical cystectomy: a multicentre multinational study. BJU Int. 2017;119:605−11 https://doi.org/10.1111/bju.13678