Catto - Figure 17
Risk Stratification
Fig. 17: This Figure displays the Kaplan-Meier curves showing the clear differences in the times-to-recurrence and -progression for the patients in the report from Sylvester et al.[18] The first obvious conclusion is that recurrence is common. Even in the low-risk population, 30–40% of the patients will have a recurrence in the bladder by 7 years. In the high-risk population, the recurrence rate reaches nearly 80%. However, as seen in the right panel, disease progression is much rarer for most of these patients. For low-risk patients, it is approximately 5%, for low-to-moderate patients it is 10%, moderate is 20%; only in high-risk patients does risk of recurrence reach 50%.
These results highlight that when talking about following up these patients, it will be of benefit and effective to try to stratify the patient population into these 2, 3, or 4 populations.
References
Sylvester RJ, van der Meijden AP, Oosterlinck W, et al. Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur Urol. 2006;49;466−77 https://doi.org/10.1016/j.eururo.2005.12.031
