Shariat - Figure 26
PDD facilitates the detection of NMIBC, notably flat forms of cancer
FIG. 26: Multiple well-done systematic reviews and meta-analyses have shown that PDD increases detection of CIS and thereby decreases recurrence rate.[31] The best quality randomized clinical trial, by Schmidbauer et al,[32] showed that PDD confers an additional relative risk reduction of almost 20%.
References
Kausch I, Sommerauer M, Montorsi F, et al. Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. Eur Urol. 2010;57:595−606 http://dx.doi.org/10.1016/j.eururo.2009.11.041
Schmidbauer J, Witjes F, Schmeller N, et al; Hexvix PCB301/01 Study Group. Improved detection of urothelial carcinoma in situ with hexaminolevulinate fluorescence cystoscopy. J Urol. 2004;171:135–8 http://dx.doi.org/10.1097/01.ju.0000100480.70769.0e
