Fig. 01 -

Title Slide

Fig. 02 -

Disclosures

Fig. 03 -

Do They Matter

Fig. 04 -

Who Do We Ask?

Fig. 05 -

EAU Guidelines

Fig. 06 -

Pathological Report

Fig. 07 -

More Guidelines

Fig. 08 -

Pathology

Fig. 09 -

Diagnosis and Treatment

Fig. 10 -

Treatment

Fig. 11 -

NCCN Guidelines

Fig. 12 -

NCCN Version 2.2017

Fig. 13 -

Variants are frequent

Fig. 14 -

Upstaging Urothelial Cancer

Fig. 15 -

Variants are Tricky

Fig. 16 -

Variants are Tricky(cont.)

Fig. 17 -

Sensitivity

Fig. 18 -

2016 WHO Classification

Fig. 19 -

Variants are Tricky (cont.)

Fig. 20 -

Response

Fig. 21 -

Concordance

Fig. 22 -

Which variants matter

Fig. 23 -

Squamous differentation

Fig. 24 -

Squamous Cell Cancer

Fig. 25 -

SCC Data

Fig. 26 -

SCC Data (Cont.)

Fig. 27 -

Urothelial vs Squamous Cell

Fig. 28 -

Histology

Fig. 29 -

Squamous Differentiation

Fig. 30 -

10 yr cystectomy rates

Fig. 31 -

NAC Study

Fig. 32 -

No Proven Role

Fig. 33 -

Adenocarcinoma

Fig. 34 -

Adenocarcinoma data

Fig. 35 -

Urachal Adenocarcinoma

Fig. 36 -

Non-urachal Adenocarcinoma

Fig. 37 -

No differentiation

Fig. 38 -

Small Cell Carinoma

Fig. 39 -

Small Cell C. Data

Fig. 40 -

Small CC. Data (Cont)

Fig. 41 -

Neoadjuvant Chemo

Fig. 42 -

Sarcomatoid Carcinoma

Fig. 43 -

Sarcomatoid Carcinoma Data

Fig. 44 -

Contemporary Treatment

Fig. 45 -

Plasmacytoid Carcinoma

Fig. 46 -

Plasmacytoid Carcinoma Data

Fig. 47 -

Outcomes

Fig. 48 -

Micropapillary Carcinoma

Fig. 49 -

Micropapillary Carcinoma Data

Fig. 50 -

Radical Cystectomy