Burger - Figure 31
Squamous Cell Cancer: NAC Study
FIG. 31: Urachal adenocarcinoma arise from the urachal remnant positioned at the bladder dome.[7] It is often a perivesical growth, and in many cases it is locally advanced, so the therapy of choice is the en bloc removal of the bladder dome, the urachal ligaments, and also the umbilicus.[19] The umbilicus must be completely excised, whereas the lower half of the bladder may be preserved. The most appropriate chemotherapy regimen is unclear, although fluorouracil-gemcitabine-cisplatin, or the FOLFOX (leucovorin, fluorouracil, oxaliplatin) regimen have been suggested.[7]
References
Klaile Y, Schlack K, Boegemann M, et al. Variant histology in bladder cancer: how it should change the management in non-muscle invasive and muscle invasive disease? Transl Androl Urol. 2016;5:692−701 https://dx.doi.org/10.21037%2Ftau.2016.06.13
Ashley RA, Inman BA, Sebo TJ, et al. Urachal carcinoma: clinicopathologic features and long-term outcomes of an aggressive malignancy. Cancer. 2006;107:712−20 https://doi.org/10.1002/cncr.22060
