Burger - Figure 17
The sensitivity of initial transurethral resection
FIG. 17: As mentioned previously, variants are clinically challenging. They behave differently, in a more aggressive fashion than conventional urothelial bladder cancer, and there is no difference between variants in NMI and muscle-invasive tumors.[7,9] The mix of variants with classical urothelial cancer may not be important. The presence of any variant portion of the tumor is associated with a poor prognosis. Our greatest challenge is that there are currently very few data available on variants.
References
Klaile Y, Schlack K, Boegemann M, et al. Variant histology in bladder cancer: how it should change the management in non-muscle invasive and muscle invasive disease? Transl Androl Urol. 2016;5:692−701 https://dx.doi.org/10.21037%2Ftau.2016.06.13
Seisen T, Compérat E, Léon P, Roupret M. Impact of histological variants on the outcomes of nonmuscle invasive bladder cancer after transurethral resection. Curr Opin Urol. 2014;24:524−31 https://doi.org/10.1097/MOU.0000000000000086
