Burger - Figure 33
Adenocarcinoma
FIG. 33: The NCCN guidelines[5] do not differentiate between the urachal and non-urachal subtypes, but they also state that there is no proven role for neoadjuvant chemotherapy and that local control by cystectomy or, again, radiotherapy is important. They stress the need for an en bloc removal in case of urachal cases, and for chemotherapy in advanced cases they suggest the FOLFOX regimen or gem-FLP (gemcitabine, fluorouracil, leucovorin, and cisplatin), then surgical consolidation in cases responsive to chemotherapy.
References
Spiess PR et al; NCCN Guidelines Version 5.2017 Panel Members Bladder Cancer. NCCN Clinical Practice Guidelines in Oncology. Bladder Cancer Version 5.2017. Fort Washington, PA: National Comprehensive Cancer Network; 2017 https://www.nccn.org/professionals/physician_gls/pdf/bladder.pdf Accessed August 11, 2017
